OK Fresno, so you’ll be coming in from the south.

Tips-
--Avoid the weekend if possible
--Fill up in Oakhurst. There are NO gas stations in the Valley. You can get gas in Wawona, that’s inside the park right on 41 - you’ll pass it on your way in/out of the valley and at Crane Flat. There are a few other spots in the park but these are the two I’m familiar with. Just know gas is expensive- that pesky law of supply and demand.
--There’s a free Valley shuttle that does a loop, it stops at all trailheads & hotels etc .
--Definitely go up to Glacier Point. It’s breath taking. There’s a parking lot which gets very crowded near sunset when all the photographers come up to get those Ansel Adams type photos.
--Stop and see the giant Sequoias in Mariposa Grove (route 41, south Entrance) or Tuolumne Grove (route 120 near Crane Flat.
--Peregrine Flacons, keep an eye out.

Have fun and let me know how it goes.