I have loved the backpack that I got from Rick Steve's. It is specifically designed for backpacking Europe (though I've not done that yet). It is very flexible. The straps can be slid back up into the bag and you can put on a single shoulder strap or none and carry by a side handle or a top handle. It has proven very durable. I was in FL one time with my family and put in a bunch of groceries and could not believe how much it could handle. Yet it's soft sided so you can put in as little as you like for the short trips. I just took a look at their site and it looks like they have some totally new bags and have added quite a bit of variety:
<a href="http://www.ricksteves.com/store/home.htm" target="_blank">http://www.ricksteves.com/store/home.htm</A>
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