Air Canada has suspended flights to CCS until further notice citing the ongoing civil unrest in Venezuela, and said it could no longer ensure the safety of its operation.
The airline, which operates three round trip flights weekly between YYZ and CCS, said the suspension is effective from March 18.
Since early February, students and hardline opposition leaders have been calling supporters onto the streets to protest against Venezuela's President Nicolas Maduro and his socialist government.
Airlines have struggled to obtain dollars in exchange for the bolivar currency as a result of long-running delays in Venezuela's 11-year-old currency control system.
Avianca Holdings, operator of Colombia's biggest airline, last week told travel agents it will cut flights between the countries' capitals to one a day from three as of March 20.
LH said earlier in the month that its 2013 financial results took a double-digit million euro hit from payment issues in Venezuela.